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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1949 1
1952 1
1962 3
1965 1
1966 4
1967 1
1968 4
1969 4
1970 10
1971 15
1972 28
1973 35
1974 55
1975 94
1976 118
1977 178
1978 162
1979 188
1980 188
1981 238
1982 211
1983 248
1984 315
1985 406
1986 417
1987 479
1988 538
1989 603
1990 672
1991 785
1992 906
1993 2083
1994 4516
1995 4966
1996 4706
1997 4434
1998 4237
1999 4231
2000 4456
2001 4447
2002 4338
2003 4400
2004 4378
2005 3868
2006 3200
2007 2936
2008 2617
2009 2502
2010 2330
2011 2327
2012 2464
2013 2495
2014 2148
2015 2044
2016 1920
2017 1610
2018 1480
2019 1451
2020 1459
2021 1488
2022 1408
2023 1248
2024 458

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93,746 results

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Page 1
Highly multiplexed subcellular RNA sequencing in situ.
Lee JH, Daugharthy ER, Scheiman J, Kalhor R, Yang JL, Ferrante TC, Terry R, Jeanty SS, Li C, Amamoto R, Peters DT, Turczyk BM, Marblestone AH, Inverso SA, Bernard A, Mali P, Rios X, Aach J, Church GM. Lee JH, et al. Science. 2014 Mar 21;343(6177):1360-3. doi: 10.1126/science.1250212. Epub 2014 Feb 27. Science. 2014. PMID: 24578530 Free PMC article.
Understanding the spatial organization of gene expression with single-nucleotide resolution requires localizing the sequences of expressed RNA transcripts within a cell in situ. Here, we describe fluorescent in situ RNA sequencing (FISSEQ), in which stably cross-lin …
Understanding the spatial organization of gene expression with single-nucleotide resolution requires localizing the sequences of expr …
Long-read sequence assembly: a technical evaluation in barley.
Mascher M, Wicker T, Jenkins J, Plott C, Lux T, Koh CS, Ens J, Gundlach H, Boston LB, Tulpová Z, Holden S, Hernández-Pinzón I, Scholz U, Mayer KFX, Spannagl M, Pozniak CJ, Sharpe AG, Šimková H, Moscou MJ, Grimwood J, Schmutz J, Stein N. Mascher M, et al. Plant Cell. 2021 Jul 19;33(6):1888-1906. doi: 10.1093/plcell/koab077. Plant Cell. 2021. PMID: 33710295 Free PMC article.
Sequence assembly of large and repeat-rich plant genomes has been challenging, requiring substantial computational resources and often several complementary sequence assembly and genome mapping approaches. ...A downsampling analysis indicated that 20-f …
Sequence assembly of large and repeat-rich plant genomes has been challenging, requiring substantial computational resources and ofte …
Non-coding Natural Antisense Transcripts: Analysis and Application.
Krappinger JC, Bonstingl L, Pansy K, Sallinger K, Wreglesworth NI, Grinninger L, Deutsch A, El-Heliebi A, Kroneis T, Mcfarlane RJ, Sensen CW, Feichtinger J. Krappinger JC, et al. J Biotechnol. 2021 Nov 10;340:75-101. doi: 10.1016/j.jbiotec.2021.08.005. Epub 2021 Aug 8. J Biotechnol. 2021. PMID: 34371054 Free article. Review.
Non-coding natural antisense transcripts (ncNATs) are regulatory RNA molecules that are overlapping with as well as complementary to other transcripts. These transcripts are implicated in a broad variety of biological and pathological processes, including tumorigenesis and …
Non-coding natural antisense transcripts (ncNATs) are regulatory RNA molecules that are overlapping with as well as complementary to …
RNA Sequencing of Formalin-Fixed and Paraffin-Embedded Tissue as a Complementary Method in Ophthalmopathology.
Schlunck G, Boneva S, Wolf J, Schlecht A, Reinhard T, Auw-Hädrich C, Lange C. Schlunck G, et al. Klin Monbl Augenheilkd. 2020 Jul;237(7):860-866. doi: 10.1055/a-1187-1590. Epub 2020 Jul 13. Klin Monbl Augenheilkd. 2020. PMID: 32659839 Review. English, German.
The high-throughput method of "Next Generation Sequencing" (NGS) allows cost-effective decoding of the nucleotide sequences of millions of RNA molecules in a sample. ...
The high-throughput method of "Next Generation Sequencing" (NGS) allows cost-effective decoding of the nucleotide sequences of …
Sequence characteristics define trade-offs between on-target and genome-wide off-target hybridization of oligoprobes.
Matveeva OV, Ogurtsov AY, Nazipova NN, Shabalina SA. Matveeva OV, et al. PLoS One. 2018 Jun 21;13(6):e0199162. doi: 10.1371/journal.pone.0199162. eCollection 2018. PLoS One. 2018. PMID: 29928000 Free PMC article.
Off-target oligoprobe's interaction with partially complementary nucleotide sequences represents a problem for many bio-techniques. The goal of the study was to identify oligoprobe sequence characteristics that control the ratio between on-target and off-targ …
Off-target oligoprobe's interaction with partially complementary nucleotide sequences represents a problem for many bio-techni …
The cDNA sequencing project.
Urushihara H, Morio T, Tanaka Y. Urushihara H, et al. Methods Mol Biol. 2006;346:31-49. doi: 10.1385/1-59745-144-4:31. Methods Mol Biol. 2006. PMID: 16957283 Review.
The Dictyostelium discoideum cDNA sequencing project started in 1995, preceding the genome sequencing project. Altogether, 14 cDNA libraries, including full-length ones, were constructed from five different stages of growth and asexual and sexual development, from w …
The Dictyostelium discoideum cDNA sequencing project started in 1995, preceding the genome sequencing project. Altogether, 14 …
Single-Cell Tagged Reverse Transcription (STRT-Seq).
Natarajan KN. Natarajan KN. Methods Mol Biol. 2019;1979:133-153. doi: 10.1007/978-1-4939-9240-9_9. Methods Mol Biol. 2019. PMID: 31028636
Single-cell RNA sequencing (scRNA-seq) has become an established approach to profile entire transcriptomes of individual cells from different cell types, tissues, species, and organisms. Single-cell tagged reverse transcription sequencing (STRT-seq) is one of the ea …
Single-cell RNA sequencing (scRNA-seq) has become an established approach to profile entire transcriptomes of individual cells from d …
RNA in situ conformation sequencing reveals novel long-range RNA structures with impact on splicing.
Margasyuk S, Kalinina M, Petrova M, Skvortsov D, Cao C, Pervouchine DD. Margasyuk S, et al. RNA. 2023 Sep;29(9):1423-1436. doi: 10.1261/rna.079508.122. Epub 2023 Jun 9. RNA. 2023. PMID: 37295923 Free PMC article.
An increasing number of human disorders are now being associated with splicing defects; hence it is essential to develop methods that assess long-range RNA structure experimentally. RNA in situ conformation sequencing (RIC-seq) is a method that recapitulates RNA structure …
An increasing number of human disorders are now being associated with splicing defects; hence it is essential to develop methods that assess …
Recovery and Analysis of Long-Read Metagenome-Assembled Genomes.
Arumugam K, Bessarab I, Haryono MAS, Williams RBH. Arumugam K, et al. Methods Mol Biol. 2023;2649:235-259. doi: 10.1007/978-1-0716-3072-3_12. Methods Mol Biol. 2023. PMID: 37258866
The development of long-read nucleic acid sequencing is beginning to make very substantive impact on the conduct of metagenome analysis, particularly in relation to the problem of recovering the genomes of member species of complex microbial communities. Here we out …
The development of long-read nucleic acid sequencing is beginning to make very substantive impact on the conduct of metagenome ana …
DNA sequence determination by hybridization: a strategy for efficient large-scale sequencing.
Drmanac R, Drmanac S, Strezoska Z, Paunesku T, Labat I, Zeremski M, Snoddy J, Funkhouser WK, Koop B, Hood L, et al. Drmanac R, et al. Science. 1993 Jun 11;260(5114):1649-52. doi: 10.1126/science.8503011. Science. 1993. PMID: 8503011
The concept of sequencing by hybridization (SBH) makes use of an array of all possible n-nucleotide oligomers (n-mers) to identify n-mers present in an unknown DNA sequence. Computational approaches can then be used to assemble the complete sequence. As a val …
The concept of sequencing by hybridization (SBH) makes use of an array of all possible n-nucleotide oligomers (n-mers) to identify n- …
93,746 results
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